Unlock a rare development opportunity in the heart of Potrero Hill with this vacant duplex at 2109-2111 22nd Street. Perfectly positioned in one of San Francisco’s most coveted neighborhoods, this property features two charming "mini-residences" offering immediate versatility: a light-filled top-floor unit with a private deck and a lower-level retreat leading to an expansive patio. Situated on a deep lot, the site serves as a blank canvas for a visionary expansion or a lush urban garden sanctuary. The location is a commuter’s dream with seamless freeway access and close proximity to Zuckerberg San Francisco General, UCSF Mission Bay, and the convenience of Whole Foods just blocks away. Add this duplex to your portfolio and take advantage of city’s current red hot rental market, or develop the property to maximize its potential in one of San Francisco’s coolest neighborhoods Potrero Hill.
Listed by Herman Chan
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License #01395481
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Golden Gate Sotheby's Int'l Re
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415-787-3450
Last updated May 23, 2026
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Source: bridgeMLS #41134522
Listing Facts
TypeMulti-family
NeighborhoodPotrero Hill
Days on Prevu35
Size752 sqft
Price per sqft$1,130
Amenities
Private Outdoor Space
Location
Mortgage Calculator
Listing History
05/13/2026
Listed by Golden Gate Sotheby's Int'l Re
$850,000
Property Details for 2109 22nd St
Exterior
Construction
Number Of Units Total: 2
Year Built: 1946
Construction Materials: Stucco
Features
Patio And Porch Features: Deck, Patio
Measurements
Building Area Total: 752
Lot Features: Other
Lot Size Acres: 0.04
Lot Size Area: 0
Lot Size Square Feet: 1,873
Lot Size Units: Acres
Financial
Taxes
Parcel Number: 4158 066
Interior
Features
Fireplace: Yes
Flooring: Tile, Carpet
Measurements
Living Area: 752
Living Area Units: Square Feet
Other
Location
Subdivision Name: Other
Utilities
Equipment
Cooling: No Air Conditioning
Heating: Fireplace(s)
Has Heating: Yes
Sewer: Public Sewer
Water Source: Public
Frequently Asked Questions
How many bedrooms does this multi-family home have?
There is bedrooms in this multi-family home at 2109 22nd St.
How does 2109 22nd St compare to other multi-family homes in Potrero Hill?
This multi-family home is listed 47% below the average price for multi-family homes in Potrero Hill and has been on the market for 14 less days than the typical home in this area.
What is the square footage on this multi-family home?
According to the MLS, this listing is 752 sqft.
2109 22nd St is a -bedroom multi-family home for sale in San Francisco CA 94107. Available on Prevu for 35 days at $850,000. This home features 752 square feet of living space, located in San Francisco. The median listing price for multi-family homes in this area is $1,223,975. Property amenities include private outdoor space. View other multi-family home listings in San Francisco.
Based on information from bridgeMLS and/or other sources. All data, including all measurements and calculations of area, is obtained from various sources and has not been, and will not be, verified by Prevu or the MLS. Information is provided exclusively for consumer's personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumer may be interested in purchasing.
Rebate estimate is indicative only and based on listing price and estimated buyer's agent commission paid by owner, if applicable. Final rebates are subject to Terms of Use and may vary due to final negotiated transaction terms.